Legend® (hyaluronate sodium) Injectable Solution

Even Healthy Joints Can Become Inflamed


Through training and competition, even the healthiest, most athletic horses become susceptible to joint inflammation. What starts as joint inflammation can quickly cascade into synovitis, and eventually osteoarthritis. Undetected or left untreated, synovitis can progress causing significant cartilage damage. Cartilage heals poorly and continued damage can result in osteoarthritis, impacting your horse's ability to compete. The goal of treatment is to normalize the inflamed joint by reducing inflammation.1


Healthy Equine Joint   Synovitis Equine Joint

Healthy Joint


Joint with Synovitis


Legend® is the only intravenous (IV) and intra-articular (IA) FDA-approved treatment for joint dysfunction of the carpus and fetlock due to non-infectious synovitis associated with osteoarthritis. Legend® is pure hyaluronic acid (HA), derived naturally through a unique biofermentation process developed by Bayer. HA has been shown to stimulate the production of normal joint fluid.2 It also may help prevent mediators of inflammation from entering the joint.1


Your veterinarian can provide the latest technology to help diagnose the lameness your horse might be suffering from. And your veterinarian can help you make the right decisions about how to best treat your equine athlete. Ask your veterinarian if Legend® is right for your horse.


Federal law restricts this drug to use by or on the order of a licensed veterinarian. For use only in horses. Do not use in horses intended for human consumption.


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Providing the best is now even more rewarding.

Visit www.legendaryoffer.com for a $30 rebate on Legend(r) (Injectable Solution.

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Rebate offer available from January 1 - December 31, 2013





1 Balazs EA, Denlinger JL: Sodium hyaluronate and joint function. Equine Vet Sci 1985;5:217-228

2 Smith, MM; Ghosh P The synthesis of hyaluronic acid by human synovial fibroblasts is influenced by the nature of the hyaluronate in the extracellular environment. Rheumatol Int. 1987;7(3):113-22.


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